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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
REEP4
All Species:
36.06
Human Site:
T117
Identified Species:
72.12
UniProt:
Q9H6H4
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H6H4
NP_079508.2
257
29395
T117
A
K
E
R
S
Y
E
T
V
L
S
F
G
K
R
Chimpanzee
Pan troglodytes
XP_001153858
257
29395
T117
A
K
E
R
S
Y
E
T
V
L
S
F
G
K
R
Rhesus Macaque
Macaca mulatta
XP_001102353
257
29523
T117
A
K
E
R
S
Y
E
T
V
L
T
F
G
K
R
Dog
Lupus familis
XP_543255
413
45887
T273
A
K
E
R
S
Y
E
T
M
L
S
F
G
K
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8K072
257
29672
T117
A
K
E
R
S
Y
E
T
M
L
S
F
G
K
R
Rat
Rattus norvegicus
Q4QQW1
257
29642
T117
A
K
E
R
S
Y
E
T
M
L
S
F
G
K
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508033
254
28447
S114
R
S
Y
E
T
V
L
S
F
G
K
R
G
L
N
Chicken
Gallus gallus
XP_421536
431
48387
T293
A
K
E
R
G
Y
E
T
M
V
N
F
G
R
Q
Frog
Xenopus laevis
NP_001086898
261
29803
S117
A
K
E
R
S
Y
E
S
F
V
N
I
G
R
K
Zebra Danio
Brachydanio rerio
Q4KMI4
268
30092
T117
A
K
D
R
S
Y
D
T
M
M
R
F
G
R
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q10010
229
26592
H93
I
L
Y
R
K
W
V
H
P
T
L
N
R
H
E
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8GXE9
258
29531
F119
L
R
A
R
A
W
D
F
F
I
F
Y
F
N
N
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
97.2
57.3
N.A.
88.3
88.7
N.A.
74.3
32.2
64.7
50
N.A.
N.A.
N.A.
37.3
N.A.
Protein Similarity:
100
100
98.4
58.5
N.A.
91
91.8
N.A.
82
41
77.3
67.5
N.A.
N.A.
N.A.
57.2
N.A.
P-Site Identity:
100
100
93.3
93.3
N.A.
93.3
93.3
N.A.
6.6
60
53.3
60
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
20
93.3
86.6
93.3
N.A.
N.A.
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
26.7
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
44.1
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
75
0
9
0
9
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
9
0
0
0
17
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
67
9
0
0
67
0
0
0
0
0
0
0
9
% E
% Phe:
0
0
0
0
0
0
0
9
25
0
9
67
9
0
0
% F
% Gly:
0
0
0
0
9
0
0
0
0
9
0
0
84
0
0
% G
% His:
0
0
0
0
0
0
0
9
0
0
0
0
0
9
0
% H
% Ile:
9
0
0
0
0
0
0
0
0
9
0
9
0
0
0
% I
% Lys:
0
75
0
0
9
0
0
0
0
0
9
0
0
50
9
% K
% Leu:
9
9
0
0
0
0
9
0
0
50
9
0
0
9
0
% L
% Met:
0
0
0
0
0
0
0
0
42
9
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
17
9
0
9
17
% N
% Pro:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% Q
% Arg:
9
9
0
92
0
0
0
0
0
0
9
9
9
25
59
% R
% Ser:
0
9
0
0
67
0
0
17
0
0
42
0
0
0
0
% S
% Thr:
0
0
0
0
9
0
0
67
0
9
9
0
0
0
0
% T
% Val:
0
0
0
0
0
9
9
0
25
17
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
17
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
17
0
0
75
0
0
0
0
0
9
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _